Hexarelin (5mg)

Hexarelin (5mg)

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ALL ARTICLES AND PRODUCT INFORMATION PROVIDED ON THIS WEBSITE ARE FOR INFORMATIONAL AND EDUCATIONAL PURPOSES ONLY. The products offered on this website are furnished for in-vitro studies only. In-vitro studies (Latin: in glass) are performed outside of the body. These products are not medicines or drugs and have not been approved by the FDA to prevent, treat or cure any medical condition, ailment or disease. Bodily introduction of any kind into humans or animals is strictly forbidden by law.

What is Hexarelin (5mg)?

Hexarelin, also known as Examorelin, stands as a synthetic analogue of ghrelin and exhibits close relation to GHRP-6. The distinction between hexarelin and GHRP-6 is subtle, involving the addition of two methyl groups to GHRP-6. Similar to numerous ghrelin analogues, hexarelin showcases oral and sublingual activity, demonstrating high selectivity. Hexarelin has been a subject of extensive research, particularly investigating its impact on the survival of heart cells under conditions of ischemia and nutrient deprivation.

 

Chemical Structure of Hexarelin (5mg)

Hexarelin, a synthetic peptide, possesses a chemical structure represented by a sequence of amino acids. Specifically, Hexarelin is a hexapeptide, comprised of six amino acids arranged in the following sequence:

H−His−D−2−methyl−Trp−Ala−Trp−D−Phe−Lys−NH2H−His−D−2−methyl−Trp−Ala−Trp−D−Phe−Lys−NH2​

In this sequence, “H” signifies the N-terminus (the starting point), and “NH_2” signifies the C-terminus (the ending point). Each letter corresponds to a specific amino acid, delineating the unique arrangement critical for its biological activity as a ghrelin analogue.

What Are the Effects of Hexarelin (5mg)?

Hexarelin, a synthetic analogue closely related to ghrelin and GHRP-6, has demonstrated a range of effects spanning cardiovascular protection, metabolic regulation, and muscular integrity. This comprehensive examination delves into the multifaceted impacts of hexarelin, providing insights into its profound influence across various physiological domains.

1. Cardioprotective Abilities

Hexarelin’s Interaction with Heart Cells

At the core of hexarelin’s effects is its direct interaction with the CD36 receptor and the growth hormone secretagogue receptor (GHSR). Studies in mice reveal hexarelin’s capacity to protect heart cells from injury during a heart attack by intervening in apoptotic pathways. This results in enhanced heart function, increased survival of heart cells, and reduced malondialdehyde production. Comparisons with GHRP-6 highlight the nuanced superiority of hexarelin in specific scenarios.

Extended Cardioprotection Beyond Acute Events

Hexarelin’s efficacy extends beyond acute cardiac events to heart failure scenarios. Detailed examinations showcase its ability to reduce oxidative stress, prevent myocardial remodeling, and enhance heart function. Molecular pathways, including the up-regulation of PTEN activity and down-regulation of protein kinase B expression, play crucial roles in these processes, impacting cell regeneration and survival.

2. Metabolic Resilience Uncovered

Diabetes and Enhanced Cardiac Function

In addition to its cardiac focus, hexarelin emerges as a potential intervention in diabetic contexts. Research in diabetic rat models demonstrates its role in improving cardiac function by modulating calcium and potassium processing in heart muscle cells, suggesting a broader application in fortifying the diabetic heart against diverse insults.

Dyslipidemia Correction and Metabolic Harmony

Hexarelin’s interaction with dyslipidemia becomes apparent in studies involving rats. GHRP-6 showcases its corrective influence on dyslipidemia amid insulin resistance, suggesting alternative therapeutic avenues for severe dyslipidemia that may challenge conventional lipid medications.

3. Muscular Safeguard: Mitigating Cachexia

Preservation Amidst Cachexia Challenges

Hexarelin’s protective role extends to muscle preservation, especially in the face of cachexia induced by illness or chemotherapy. By regulating calcium dynamics and mitochondrial function, hexarelin exhibits promise in mitigating chemotherapy-induced muscle loss. This positions GHRP-6 as a potential safeguard against pathological weight loss and muscle degradation, crucial for maintaining overall physiological integrity.

4. Scientific Inquiry: Hexarelin’s Catalyst Role

Advancing Cardiovascular Research

As a catalyst in cardiovascular research, hexarelin plays a crucial role in heart health. Its role extends beyond immediate applications, offering insights into novel pathways, particularly in conditions like cardiac remodeling. Ethical research practices emphasize its exclusive role in advancing scientific knowledge and potential therapeutic horizons.

COA

Certificate of Analysis

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HPLC

High Performance Liquid Chromatography

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